Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843866 | 1.00 | TK1 (0.54) | TK1BCHEABCG2ABCB1RNASE1 | |
| SCHEMBL2056775 | 0.89 | POLB (0.61) | TK1BCHE | |
| SCHEMBL8999366 | 0.89 | POLB (0.61) | TK1BCHE | |
| SCHEMBL9156285 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL22512589 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1RNASE1 | |
| SCHEMBL9157298 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL9011675 | 0.89 | TK1 (0.57) | TK1ABCG2ABCB1 | |
| SCHEMBL12718357 | 0.88 | TK1 (0.52) | TK1BCHEABCG2ABCB1RNASE1 | |
| SCHEMBL19983719 | 0.88 | ABCG2 (0.64) | TK1ABCG2ABCB1 | |
| SCHEMBL9333405 | 0.87 | BCHE (0.42) | TK1BCHEABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450585-A2 | Process for the manufacture of 2-deoxy-D-threo-pentofuranosides, intermediates for their manufacture and their use | CHEMPROSA, CHEMISCHE PRODUKTE SAISCHEK GmbH (AT) | 1991-10-09 | — | — | EP | disclosed |