SCHEMBL8999841

SCHEMBL8999841

CCOC(=O)CC(=O)OCC(CC)(COC(=O)CC(=O)OCC)COC(=O)CC(=O)OCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.65
MGAM O43451 1/20 0.65
SI P14410 1/20 0.65
MGAM2 Q2M2H8 1/20 0.65
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 1/20 0.43
THRB P10828 1/20 0.38
PPID Q08752 1/20 0.38
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALOX15 P16050 2/20 0.36
SOAT1 P35610 1/20 0.36
NLRP3 Q96P20 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28497741 0.94 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21652621 0.88 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL651229 0.83 MGAM (0.46) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8636 0.81 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331824 0.81 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1864301 0.81 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331187 0.81 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1330550 0.81 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL14375218 0.80 GAA (0.68) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL9001040 0.79 NAAA (0.41) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286534-B2 Binder for an aqueous coating composition ALLNEX AUSTRIA GMBH (AT) 2025-04-29 US disclosed
US-20220098406-A1 BINDER FOR AN AQUEOUS COATING COMPOSITION ALLNEX AUSTRIA GMBH (AT) 2022-03-31 US disclosed
EP-3918017-A1 BINDER FOR AN AQUEOUS COATING COMPOSITION Allnex Austria GmbH (AT) 2021-12-08 EP disclosed
US-20210129104-A1 PROCESS FOR PREPARING MICROCAPSULES FIRMENICH SA (CH) 2021-05-06 US disclosed
EP-3712190-A1 BINDER FOR AN AQUEOUS COATING COMPOSITION ALLNEX AUSTRIA GmbH (AT) 2020-09-23 EP disclosed
WO-2020157228-A1 BINDER FOR AN AQUEOUS COATING COMPOSITION ALLNEX AUSTRIA GMBH (AT) 2020-08-06 WO disclosed
EP-3689986-A1 BINDER FOR AQUEOUS COATING COMPOSITIONS ALLNEX AUSTRIA GmbH (AT) 2020-08-05 EP disclosed
US-5567761-A BLEND OF ACETOACETYLATED POLYMER AND A POLYACRYLATE; GLOSS, HARDNESS GUERTIN BROS. COATINGS AND SEALANTS LTD. (CA) 1996-10-22 US disclosed
WO-1995016749-A1 AQUEOUS TWO-PART ISOCYANATE-FREE CURABLE, POLYURETHANE RESIN SYSTEMS GUERTIN BROS. COATINGS AND SEALANTS LTD. (CA) 1995-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129104-A1 PROCESS FOR PREPARING MICROCAPSULES C5, CAPRIN1, EXOSC9 GAA 1649/4885MGAM 518/4885SI 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.