Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357217 | 0.85 | KIF11 (0.40) | KIF11HSD17B3ALDH1A1HTTNR1I2 | |
| SCHEMBL11142828 | 0.83 | ALDH1A1 (0.53) | KIF11ALDH1A1HTTNR1I2LMNA | |
| SCHEMBL30102540 | 0.83 | ALDH1A1 (0.53) | KIF11ALDH1A1HTTNR1I2LMNA | |
| SCHEMBL3192593 | 0.82 | KIF11 (0.38) | KIF11HSD17B3ALDH1A1HTTNR1I2 | |
| SCHEMBL10357522 | 0.82 | KIF11 (0.38) | KIF11HSD17B3ALDH1A1HTTNR1I2 | |
| SCHEMBL27090249 | 0.80 | ESR1 (0.50) | ALDH1A1HTTLMNAARGAA | |
| SCHEMBL8405886 | 0.79 | RXRA (0.54) | CYP2C9ARRXRARXRBRXRG | |
| SCHEMBL24436810 | 0.77 | KDM4E (0.46) | HSD17B3ALDH1A1HSD17B10GAARXRA | |
| SCHEMBL3022860 | 0.77 | KIF11 (0.52) | KIF11HSD17B3ALDH1A1HTTNR1I2 | |
| SCHEMBL30368360 | 0.77 | KIF11 (0.52) | KIF11HSD17B3ALDH1A1HTTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |