Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001881 | 0.94 | KAT2B (0.55) | KAT2BNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL8997016 | 0.87 | KAT2B (0.57) | KAT2BNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14960116 | 0.84 | KAT2B (0.59) | KAT2BNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8654854 | 0.84 | KAT2B (0.66) | KAT2BNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9000222 | 0.83 | ALDH1A1 (0.52) | KAT2BALDH1A1TSHRTDP1MAPT | |
| Hydrochloric Acid SCHEMBL8645147 | 0.82 | KAT2B (0.67) | KAT2BNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8647822 | 0.82 | KAT2B (0.60) | KAT2BNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL8997010 | 0.81 | KAT2B (0.56) | KAT2BNPC1RAB9AALDH1A1MAPT | |
| Diethanolamine SCHEMBL198856 | 0.81 | KAT2B (0.60) | KAT2BNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL11720943 | 0.80 | KAT2B (0.61) | KAT2BNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504637-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| US-9248086-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2015-06-25 | — | — | US | disclosed |
| US-8932370-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140326269-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-11-06 | — | — | US | disclosed |
| US-8758451-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2014-01-16 | — | — | US | disclosed |
| US-8444715-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120272990-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2012-11-01 | — | — | US | disclosed |
| US-8187340-B2 | Coloring agents and methods of use thereof | LIVING PROOF, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| WO-2011084803-A2 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120272990-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
| US-20110154583-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
| US-20160106648-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
| US-20140013520-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
| US-20150174026-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
| US-20140326269-A1 | COLORING AGENTS AND METHODS OF USE THEREOF | MPO, HLA-C, ADH7 | KAT2B 417/4885NPC1 2041/4885RAB9A 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.