Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835675 | 0.85 | GRM6 (0.46) | IDO1GRM6MAPTALDH1A1KDM4E | |
| SCHEMBL9016796 | 0.76 | GRIA4 (0.45) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9016795 | 0.73 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Water SCHEMBL27930773 | 0.72 | GPR3 (0.65) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Water SCHEMBL8091139 | 0.72 | GPR3 (0.65) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11260561 | 0.72 | GRIA4 (0.40) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Water SCHEMBL28769669 | 0.71 | KDM4E (0.62) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11331315 | 0.71 | LIMK1 (0.46) | IDO1GRM6MAPTALDH1A1KDM4E | |
| SCHEMBL29374932 | 0.70 | GPR3 (0.68) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4696033 | 0.70 | GPR3 (0.68) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013771-A | SUBSTITUTED 2-AMINOTHIOCHROMONES | WARNER-LAMBERT COMPANY (US) | 1977-03-22 | — | — | US | claimed |
| EP-0552493-B1 | Thiochromenone derivatives as antidotes and herbicidal agents containing them | BASF AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5378677-A | Applying with cyclohexenone derivative | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| EP-0552493-A1 | Thiochromenone derivatives as antidotes and herbicidal agents containing them | BASF Aktiengesellschaft (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4013771-A | SUBSTITUTED 2-AMINOTHIOCHROMONES | WARNER-LAMBERT COMPANY (US) | 1977-03-22 | — | — | US | disclosed |