Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000153 | 0.73 | IDO1 (0.44) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL9016796 | 0.73 | GRIA4 (0.45) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL9865595 | 0.71 | PSMB8 (0.38) | ALDH1A1KDM4EL3MBTL1MAPK1NPSR1 | |
| SCHEMBL11260561 | 0.70 | GRIA4 (0.40) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL9016732 | 0.68 | MPI (0.46) | ALDH1A1MAPTKDM4EL3MBTL1LMNA | |
| Water SCHEMBL8091139 | 0.67 | GPR3 (0.65) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| Water SCHEMBL27930773 | 0.67 | GPR3 (0.65) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| Water SCHEMBL28769669 | 0.65 | KDM4E (0.62) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL12750484 | 0.65 | GPR3 (0.44) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL4696033 | 0.65 | GPR3 (0.68) | ALDH1A1MAPTKDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481441-B1 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN SEIYAKU KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5244892-A | Pseudomonas | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0481441-A2 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |