Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000353 | 0.83 | CYP11B2 (0.50) | CYP11B1CYP11B2CYP19A1CHEK1 | |
| SCHEMBL4822196 | 0.80 | PTGS2 (0.42) | CYP11B1CYP11B2PTGS2ATMHDAC1 | |
| SCHEMBL9000546 | 0.79 | CHEK1 (0.51) | CYP19A1CHEK1GRM4MEN1ALDH1A1 | |
| SCHEMBL9000486 | 0.78 | KDM1A (0.42) | CYP11B1CYP11B2ATMHDAC1KDM1A | |
| SCHEMBL9000376 | 0.77 | CA1 (0.50) | HDAC1CYP19A1CHEK1HDAC6GRM4 | |
| SCHEMBL2106457 | 0.76 | MKNK1 (0.47) | CYP11B1CYP11B2PTGS2ATMMKNK1 | |
| SCHEMBL30345862 | 0.76 | MKNK1 (0.47) | CYP11B1CYP11B2PTGS2ATMMKNK1 | |
| SCHEMBL5456890 | 0.76 | ATM (0.45) | CYP11B1CYP11B2PTGS2ATMHDAC1 | |
| SCHEMBL11445820 | 0.76 | PTGS2 (0.56) | CYP11B1CYP11B2PTGS2ATMMKNK1 | |
| SCHEMBL8427305 | 0.73 | PTGS2 (0.41) | CYP11B1CYP11B2PTGS2ATMHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516409-B1 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5416213-A | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0516409-A2 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-02 | — | — | EP | disclosed |