Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SCN4A | P35499 | 4/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707482 | 0.87 | SMN1; SMN2 (0.38) | ACHESMN1; SMN2GAALMNAAR | |
| SCHEMBL9805918 | 0.78 | ACHE (0.52) | ACHESMN1; SMN2GAATRPA1ATM | |
| SCHEMBL22564870 | 0.76 | ACHE (0.50) | ACHESMN1; SMN2GAATRPA1ATM | |
| SCHEMBL9190117 | 0.76 | ACHE (0.50) | ACHESMN1; SMN2GAATRPA1ATM | |
| SCHEMBL10974107 | 0.75 | HSD11B1 (0.35) | SMN1; SMN2ARTRPA1KIF11ALDH1A1 | |
| SCHEMBL20565401 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2LMNAHTR2AALDH1A1TSHR | |
| SCHEMBL900168 | 0.75 | KDM4E (0.30) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL21614301 | 0.74 | SMN1; SMN2 (0.33) | SMN1; SMN2HTR2AALDH1A1KDM4ETDP1 | |
| SCHEMBL19673759 | 0.73 | ACHE (0.43) | ACHELMNAARCYP1A2CYP2A6 | |
| SCHEMBL16707480 | 0.71 | KDM4E (0.33) | SMN1; SMN2TRPA1ATMHTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |