SCHEMBL900222

SCHEMBL900222

O=S(=O)=C1N=c2ccccc2=N1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.33
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3717922 0.70 MEN1 (0.35) MEN1NPC1POLBMAPTRAB9A
SCHEMBL30858393 0.67
SCHEMBL28072669 0.67 MEN1 (0.35) MEN1NPC1POLBMAPTRAB9A
SCHEMBL37950 0.67 MEN1 (0.35) MEN1NPC1POLBMAPTRAB9A
SCHEMBL317892 0.67 MAPT (0.40) MEN1NPC1POLBMAPTRAB9A
SCHEMBL7398024 0.67 MAPT (0.39) MEN1NPC1POLBMAPTRAB9A
SCHEMBL21316061 0.65 MAPT (0.41) MEN1NPC1POLBMAPTRAB9A
SCHEMBL640436 0.65 APAF1 (0.33) MEN1NPC1POLBMAPTRAB9A
Hydrochloric Acid SCHEMBL4647777 0.65 APAF1 (0.33) MEN1NPC1POLBMAPTRAB9A
SCHEMBL21359837 0.65 MAPT (0.38) MEN1NPC1POLBMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026944-A Preparation method and application of dialkyl sulfonyl benzimidazole compound 广东方中高新材料有限公司 2024-05-14 CN claimed
CN-122056845-A Esomeprazole enteric capsule, and preparation method and application thereof 通化万通药业股份有限公司 2026-05-19 CN disclosed
US-20260034105-A1 Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY (CN) 2026-02-05 US disclosed
CN-116807990-B Esomeprazole magnesium enteric capsule and preparation method thereof 桂林华信制药有限公司 2024-09-24 CN disclosed
CN-118026944-A Preparation method and application of dialkyl sulfonyl benzimidazole compound 广东方中高新材料有限公司 2024-05-14 CN disclosed
CN-118026944-A Preparation method and application of dialkyl sulfonyl benzimidazole compound 广东方中高新材料有限公司 2024-05-14 CN disclosed
CN-118026944-A Preparation method and application of dialkyl sulfonyl benzimidazole compound 广东方中高新材料有限公司 2024-05-14 CN disclosed
CN-118026939-A Preparation method and application of fluorine-containing alkyl sulfonyl benzimidazole compound 广东方中高新材料有限公司 2024-05-14 CN disclosed
CN-117142437-A Preparation method of sulfuryl fluoride 内蒙古图微新材料科技有限公司 2023-12-01 CN disclosed
CN-116807990-A Esomeprazole magnesium enteric capsule and preparation method thereof 桂林华信制药有限公司 2023-09-29 CN disclosed
US-4338329-A COMBATTING RHINOVIRUSES ELI LILLY AND COMPANY (US) 1982-07-06 US disclosed
US-4316021-A VIRICIDES ELI LILLY AND COMPANY (US) 1982-02-16 US disclosed
US-4289782-A PARTICULARLY FOR INHIBITING GROWTH OF RHINOVIRUSES ELI LILLY AND COMPANY (US) 1981-09-15 US disclosed
US-4243813-A VIRICIDES ELI LILLY AND COMPANY (US) 1981-01-06 US disclosed
US-4230868-A α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles ELI LILLY AND COMPANY (US) 1980-10-28 US disclosed
US-4196125-A VIRICIDES ELI LILLY AND COMPANY (US) 1980-04-01 US disclosed
US-4174454-A VIRICIDES ELI LILLY AND COMPANY (US) 1979-11-13 US disclosed
US-4118742-A VIRICIDES ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4118573-A ANTIVIRAL AGENTS ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4018790-A VIRICIDES ELI LILLY AND COMPANY (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034105-A1 Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors PIK3R1, PIK3R4, PIK3R2 G6PD 3381/4885MEN1 4252/4885NPC1 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.