Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316061 | 0.72 | MAPT (0.41) | MAPTALDH1A1TDP1NPC1POLB | |
| SCHEMBL11011716 | 0.67 | MEN1 (0.42) | MAPTALDH1A1TDP1NPC1POLB | |
| SCHEMBL900222 | 0.67 | G6PD (0.33) | MAPTTDP1NPC1POLBRAB9A | |
| SCHEMBL9541649 | 0.67 | FLT1 (0.40) | MAPTALDH1A1TDP1NPC1POLB | |
| SCHEMBL1696827 | 0.67 | ALDH1A1 (0.30) | MAPTALDH1A1HPGDHIF1AHSD17B10 | |
| SCHEMBL3499657 | 0.67 | CASP1 (0.39) | MAPTALDH1A1TDP1NPC1POLB | |
| SCHEMBL211306 | 0.67 | TSHR (0.39) | ALDH1A1TDP1NPC1POLBRAB9A | |
| SCHEMBL6094001 | 0.67 | MAPT (0.30) | MAPT | |
| SCHEMBL858858 | 0.67 | MAPT (0.34) | MAPTALDH1A1TDP1NPC1L3MBTL1 | |
| SCHEMBL37950 | 0.67 | MEN1 (0.35) | MAPTTDP1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | claimed |
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | disclosed |
| WO-2001042224-A1 | CARBOXYAMIDO DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-06-14 | — | — | WO | disclosed |