Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002614 | 0.87 | F10 (0.41) | RAB9ATP53HSD17B10MAPTALDH1A1 | |
| SCHEMBL9002157 | 0.78 | GAA (0.57) | RAB9AHSD17B10MAPTALDH1A1KDM4E | |
| SCHEMBL9002172 | 0.73 | MAPT (0.43) | HSD17B10MAPTALDH1A1POLBTDP1 | |
| Hydrochloric Acid SCHEMBL9001908 | 0.72 | MAPT (0.42) | HSD17B10MAPTALDH1A1POLBTDP1 | |
| SCHEMBL9002528 | 0.69 | ALDH1A1 (0.41) | HSD17B10MAPTALDH1A1POLBTDP1 | |
| SCHEMBL9002349 | 0.68 | MAPT (0.44) | RAB9ATP53HSD17B10MAPTALDH1A1 | |
| SCHEMBL9001984 | 0.67 | MAPK1 (0.46) | RAB9ATP53HSD17B10MAPTALDH1A1 | |
| SCHEMBL9002171 | 0.67 | MAPT (0.41) | HSD17B10MAPTALDH1A1POLBTDP1 | |
| SCHEMBL9002013 | 0.67 | POLB (0.37) | HSD17B10MAPTALDH1A1POLBTDP1 | |
| SCHEMBL9001911 | 0.67 | RECQL (0.43) | HSD17B10MAPTALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| US-5244908-A | Calmodulin inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |