SCHEMBL9002573

SCHEMBL9002573

CCOC(=O)N1C(C)(C)CC(NC(=O)C(=O)NN)CC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
CASP6 P55212 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
RECQL P46063 1/20 0.31
TSHR P16473 1/20 0.31
SMYD3 Q9H7B4 1/20 0.30
LMNA P02545 2/20 0.30
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9419557 0.82 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1KMT2ANPSR1
SCHEMBL8337045 0.80 GAA (0.33) KDM4EKMT2AGAASMN1; SMN2
SCHEMBL9002710 0.77 THRB (0.36) ALDH1A1KDM4EL3MBTL1THRBATM
SCHEMBL9002550 0.77 HDAC4 (0.36) KDM4EKMT2AGAASMN1; SMN2TSHR
SCHEMBL9003080 0.77 GAA (0.39) ALDH1A1KDM4EKMT2AGAASMN1; SMN2
SCHEMBL9419599 0.77 MAOB (0.31) KDM4EGAASMN1; SMN2
SCHEMBL9580468 0.76 ALOX15 (0.34) ALDH1A1KDM4EL3MBTL1THRBATM
SCHEMBL10991831 0.75 GAA (0.39) ALDH1A1KDM4EL3MBTL1THRBATM
SCHEMBL9643928 0.74 EZH2 (0.38) KDM4EGAASMN1; SMN2
SCHEMBL9419579 0.73 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
US-5318851-A Curable composition with auxiliary curing agent; coatings ELF ATOCHEM N.A., INC. (US) 1994-06-07 US disclosed
US-5300545-A Mixing with a N-(2,2,6,6-tetraalkyl-4-piperidinyl)amide-hydrazides stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-05 US disclosed
US-5214147-A Reacting piperdinyl half-ester half-amide with hydrazine; heat and light stabilizers for anhydride copolymers by chemical attachment of hydrazide functional group ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-05-25 US disclosed
EP-0516192-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-12-02 EP disclosed
EP-0507333-A2 Epoxy resins containing bound light stabilizing groups ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-10-07 EP disclosed
US-5132387-A Polyme bound ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-21 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
US-5101033-A Piperidinyl-N-aminooxamides ATOCHEM NORTH AMERICA, INC. (US) 1992-03-31 US disclosed
EP-0410970-A4 REACTIVE HINDERED AMINE LIGHT STABILIZERS 1991-07-31 EP disclosed
EP-0410970-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS. ATOCHEM NORTH AMERICA (US) 1991-02-06 EP disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
WO-1990009408-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed