SCHEMBL9002576

SCHEMBL9002576

C=CCS(=O)(=O)c1ccccc1NN

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.55
CA1 P00915 7/20 0.55
CA9 Q16790 5/20 0.55
CA12 O43570 3/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA14 Q9ULX7 2/20 0.34
PTGES2 Q9H7Z7 5/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347320 0.78 CA1 (0.62) CA2CA1CA9CA12CA6
SCHEMBL27972245 0.77 CA1 (0.48) CA2CA1ALDH1A1KDM4EKMT2A
SCHEMBL10585791 0.77 ALDH1A1 (0.49) CA2CA1CA9CA12CA6
SCHEMBL2358800 0.77 GAA (0.52) CA2CA1CA9CA12CA6
SCHEMBL27346903 0.75 KDM4E (0.45) CA2CA1CA9CA12CA6
SCHEMBL1204858 0.74 ALDH1A1 (0.54) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL27601611 0.73 ALDH1A1 (0.47) CA2CA1CA9CA5AALDH1A1
SCHEMBL707747 0.73 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL4277651 0.73 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1LMNAMAPT
SCHEMBL11079398 0.73 ALDH1A1 (0.49) CA2CA1CA9CA12CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US claimed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP claimed
JP-6234956-A None JP disclosed
EP-0731793-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-09-18 EP disclosed
WO-1995015315-A1 1,5-DIPHENYL PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-06-08 WO disclosed
JP-H06234956-A IMPROVEMENT OF ANAEROBIC ADHESIVE CECA SA 1994-08-23 JP disclosed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed