SCHEMBL2358800

SCHEMBL2358800

C=CCS(=O)(=O)c1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
CA9 Q16790 3/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CYP2C9 P11712 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
ALDH1A1 P00352 3/20 0.49
KDM4E B2RXH2 1/20 0.49
KYNU Q16719 2/20 0.47
HTR6 P50406 1/20 0.46
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11784224 0.82 ALDH1A1 (0.48) GAACA9CA12CA1CA2
SCHEMBL10585791 0.81 ALDH1A1 (0.49) CA9CA12CA1CA2CA4
SCHEMBL8717712 0.78 ALDH1A1 (0.42) GAACA9CA12CA1CA2
SCHEMBL1204858 0.78 ALDH1A1 (0.54) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL10630409 0.78 ALDH1A1 (0.40) GAACA9CA12CA1CA2
SCHEMBL11079398 0.77 ALDH1A1 (0.49) GAACA9CA12CA1CA2
SCHEMBL370697 0.77 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL4277651 0.77 ALDH1A1 (0.49) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL707747 0.77 ALDH1A1 (0.49) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL10351904 0.77 ALDH1A1 (0.49) GAAALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013020917-A1 Ophthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide CARL ZEISS MEDITEC AG (DE) 2013-02-14 WO claimed
JP-63270658-A None JP disclosed
EP-2846848-B1 OPHTHALMIC VISCOELASTIC DEVICE ZEISS CARL MEDITEC AG (DE) 2018-03-07 EP disclosed
US-20150119356-A1 Ophthalmic Viscoelastic Device CARL ZEISS MEDITEC AG (DE) 2015-04-30 US disclosed
EP-2846848-A1 OPHTHALMIC VISCOELASTIC DEVICE Carl Zeiss Meditec AG (DE) 2015-03-18 EP disclosed
US-8642640-B2 1-phenylpyrrole derivatives EXELIXIS, INC. (US) 2014-02-04 US disclosed
EP-2349996-B1 1-PHENYLPYRROLE COMPOUNDS EXELIXIS INC (US) 2014-01-01 EP disclosed
WO-2013167632-A1 OPHTHALMIC VISCOELASTIC DEVICE CARL ZEISS MEDITEC AG (DE) 2013-11-14 WO disclosed
WO-2013020917-A1 Ophthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide CARL ZEISS MEDITEC AG (DE) 2013-02-14 WO disclosed
US-20110263544-A1 1-Phenylpyrrole Derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-10-27 US disclosed
EP-0140252-A2 Polyazo dyes BASF Aktiengesellschaft (DE) 1985-05-08 EP disclosed
US-4491543-A BROWN DYES ON LEATHER BASF AKTIENGESELLSCHAFT (DE) 1985-01-01 US disclosed
EP-0068245-B1 DYESTUFFS CONTAINING SULPHONIC ACID GROUPS BASF Aktiengesellschaft (DE) 1984-10-31 EP disclosed
EP-0031099-B1 COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES BASF Aktiengesellschaft (DE) 1984-07-18 EP disclosed
EP-0078007-A1 Metallised polyazo dyestuffs BASF Aktiengesellschaft (DE) 1983-05-04 EP disclosed
EP-0068245-A1 Dyestuffs containing sulphonic acid groups BASF Aktiengesellschaft (DE) 1983-01-05 EP disclosed
EP-0066714-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-12-15 EP disclosed
EP-0031099-A2 Compounds with reactive rests and their use in dyeing fibres BASF Aktiengesellschaft (DE) 1981-07-01 EP disclosed
US-4163659-A HERBICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-08-07 US disclosed
US-4076519-A N-substituted perfluoroalkanesulfonamides as herbicides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263544-A1 1-Phenylpyrrole Derivatives REN, AGTR1, NR3C2 GAA 4795/4885CA9 4135/4885CA12 4557/4885
US-20150119356-A1 Ophthalmic Viscoelastic Device UACA, ICAM1, VIM GAA 2851/4885CA9 3042/4885CA12 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.