SCHEMBL900296

SCHEMBL900296

Nc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.76
TSHR P16473 3/20 0.76
CYP3A4 P08684 2/20 0.76
LMNA P02545 2/20 0.76
MPO P05164 1/20 0.76
CYP2C9 P11712 1/20 0.76
ALDH1A1 P00352 3/20 0.62
CA6 P23280 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA3 P07451 1/20 0.62
THRB P10828 1/20 0.62
ALOX15 P16050 1/20 0.62
CASP1 P29466 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
PKM P14618 3/20 0.57
CA2 P00918 5/20 0.56
CA1 P00915 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL4156538 0.89 HTR6 (0.60) HTR6TSHRCYP3A4LMNAMPO
Dapsone SCHEMBL2031998 0.87 HTR6 (0.89) HTR6TSHRCYP3A4LMNAMPO
SCHEMBL29724901 0.87 GAA (0.67) HTR6TSHRCYP3A4LMNAMPO
SCHEMBL124022 0.87 GAA (0.67) HTR6TSHRCYP3A4LMNAMPO
SCHEMBL3792342 0.87 GAA (0.67) HTR6TSHRCYP3A4LMNAMPO
SCHEMBL18838 0.87 GAA (0.67) HTR6TSHRCYP3A4LMNAMPO
Dapsone SCHEMBL21428 0.87 HTR6 (1.00) HTR6TSHRCYP3A4LMNAMPO
Dapsone SCHEMBL5055312 0.87 HTR6 (1.00) HTR6TSHRCYP3A4LMNAMPO
SCHEMBL324893 0.87 HTR6 (1.00) HTR6TSHRCYP3A4LMNAMPO
Dapsone SCHEMBL1219599 0.87 HTR6 (1.00) HTR6TSHRCYP3A4LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116804027-A Benzoxazine type phthalonitrile monomer containing siloxane chain segment and preparation method thereof 江苏君澄空间科技有限公司 2023-09-26 CN claimed
CN-116695435-A Carbon fiber, preparation method thereof and composite material containing carbon fiber 江苏君澄空间科技有限公司 2023-09-05 CN claimed
CN-116675953-A Crosslinkable Networks and Thermoset Polymers from Functionalized Polyetherimides 高新特殊工程塑料全球技术有限公司 2023-09-01 CN claimed
CN-113710725-B Crosslinkable networks from functionalized polyetherimides and thermoset polymers therefrom 高新特殊工程塑料全球技术有限公司 2023-07-07 CN claimed
US-20150274965-A1 Laminate for a Printed Circuit Board TICONA LLC 2015-10-01 US claimed
US-20150275034-A1 Aromatic Polyester Solution TICONA LLC 2015-10-01 US claimed
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
US-20150275033-A1 Aromatic Polyester Film TICONA LLC 2015-10-01 US claimed
US-20150274884-A1 Fluorinated Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
US-9145469-B2 Aromatic polyester containing a biphenyl chain disruptor TICONA LLC (US) 2015-09-29 US claimed
EP-2834290-A1 THERMOTROPIC LIQUID CRYSTALLINE POWDER Ticona LLC (US) 2015-02-11 EP claimed
US-20140178654-A1 Porous Substrate Impregnated with an Aromatic Polyester TICONA, LLC (US) 2014-06-26 US claimed
US-20140178705-A1 Aromatic Polyester Coatings and Laminates TICONA LLC (US) 2014-06-26 US claimed
US-20140087149-A1 SOLUBLE AROMATIC POLYMER TICONA LLC (US) 2014-03-27 US claimed
US-20140087165-A1 Aromatic Polyester Containing a Biphenyl Chain Disruptor TICONA LLC (US) 2014-03-27 US claimed
US-20140087086-A1 Thermotropic Liquid Crystalline Powder TICONA LLC (US) 2014-03-27 US claimed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-116804027-A Benzoxazine type phthalonitrile monomer containing siloxane chain segment and preparation method thereof 江苏君澄空间科技有限公司 2023-09-26 CN disclosed
US-4059567-A High molecular weight polytriazines of soluble polymeric N-cyano-isourea ethers BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-3960812-A DIELECTRICS, MECHANICAL PROPERTIES CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed