Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899956 | 0.92 | PDK2 (0.40) | PDK2GSRCA1CA2GABRA1 | |
| SCHEMBL899485 | 0.80 | PDK2 (0.47) | PDK2GABRA1GABRB2TRPA1LMNA | |
| SCHEMBL899918 | 0.77 | PDK2 (0.43) | PDK2GSRCA1CA2TRPA1 | |
| SCHEMBL900122 | 0.76 | PDK2 (0.45) | PDK2TRPA1LMNAMAPTNPC1 | |
| SCHEMBL2884823 | 0.76 | ESR1 (0.50) | PDK2CA1CA2GABRA1GABRB1 | |
| SCHEMBL29683736 | 0.75 | PDK2 (0.51) | PDK2TRPA1LMNAMAPTNPC1 | |
| SCHEMBL900437 | 0.72 | TRPA1 (0.44) | PDK2TRPA1LMNAMAPTNPC1 | |
| SCHEMBL899538 | 0.72 | ESR1 (0.60) | PDK2TRPA1LMNAMAPTALDH1A1 | |
| SCHEMBL2854879 | 0.71 | GSR (0.61) | GSRCA1CA2GABRA1GABRB1 | |
| SCHEMBL23655327 | 0.67 | PDK2 (0.61) | PDK2TRPA1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042058-A1 | IMPACT RESISTANCE MODIFIERS FOR EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2012-04-05 | — | — | WO | disclosed |