Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900307 | 0.92 | PDK2 (0.40) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL899485 | 0.87 | PDK2 (0.47) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL900437 | 0.76 | TRPA1 (0.44) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL18100870 | 0.73 | ESR1 (0.41) | PDK2LMNAMAPTSMN1; SMN2EGFR | |
| SCHEMBL18101032 | 0.73 | ESR1 (0.43) | PDK2ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL899918 | 0.72 | PDK2 (0.43) | PDK2ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL2884823 | 0.72 | ESR1 (0.50) | PDK2ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL900122 | 0.72 | PDK2 (0.45) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL29683736 | 0.71 | PDK2 (0.51) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL900106 | 0.70 | ESR1 (0.51) | PDK2LMNAMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042058-A1 | IMPACT RESISTANCE MODIFIERS FOR EPOXY RESIN COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2012-04-05 | — | — | WO | disclosed |