Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181564 | 0.92 | REN (0.39) | RENCTSSAKT1CTSLCTSB | |
| SCHEMBL29131383 | 0.90 | CA12 (0.47) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL4918687 | 0.90 | CA12 (0.47) | RENCTSSAKT1CCKBRKDM4E | |
| SCHEMBL29543867 | 0.90 | CA12 (0.47) | RENCTSSAKT1CCKBRKDM4E | |
| Hydrochloric Acid SCHEMBL27571838 | 0.87 | GNPAT (0.49) | PTPN1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL5052616 | 0.85 | PTGER4 (0.45) | CTSSCTSLKDM4EMEN1ALDH1A1 | |
| SCHEMBL6425766 | 0.82 | PKM (0.40) | RENCTSSAKT1CTSLCTSB | |
| SCHEMBL22117446 | 0.82 | CTSK (0.57) | RENCTSSAKT1CTSLCTSB | |
| SCHEMBL22117445 | 0.82 | CTSK (0.57) | RENCTSSAKT1CTSLCTSB | |
| SCHEMBL22117444 | 0.82 | CTSK (0.57) | RENCTSSAKT1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731841-A1 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | Cangene Corporation (CA) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995017512-A2 | PROTEASES FROM STREPTOMYCES AND USE THEREOF IN PROTEIN EXPRESSION SYSTEMS | CANGENE CORPORATION (CA) | 1995-06-29 | — | — | WO | disclosed |