SCHEMBL9003570

SCHEMBL9003570

O=[N+]([O-])c1ccc(C[SH2+])cc1.c1ccc(C[B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
PTPRF P10586 1/20 0.44
PTPN2 P17706 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN11 Q06124 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SIGMAR1 Q99720 1/20 0.44
ALDH1A1 P00352 5/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.42
CRHBP P24387 2/20 0.42
CRHR2 Q13324 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13946243 0.75 CYP1A2 (0.67) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL9003500 0.74 MEN1 (0.39) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL27583120 0.73 ALDH1A1 (0.65) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL307003 0.73 CALM1 (0.43) ALDH1A1SMN1; SMN2TSHRTAAR1LOXL2
SCHEMBL267666 0.71 ALDH1A1 (0.70) CYP1A2CYP2C19PTPRFPTPN2PTPN1
Lithium Ion SCHEMBL8757501 0.71 CALM1 (0.41) ALDH1A1SMN1; SMN2TSHRTAAR1LOXL2
SCHEMBL17417857 0.71 CALM1 (0.41) ALDH1A1SMN1; SMN2TSHRTAAR1LOXL2
Ammonia Solution, Strong SCHEMBL15569691 0.71 CALM1 (0.41) ALDH1A1SMN1; SMN2TSHRTAAR1LOXL2
SCHEMBL1163856 0.71 SIGMAR1 (0.65) CYP1A2CYP2C19PTPRFPTPN2PTPN1
SCHEMBL1163877 0.71 SIGMAR1 (0.65) CYP1A2CYP2C19PTPRFPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed