Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888653 | 0.84 | KDM4E (0.41) | HTTUSP2NPSR1POLBTSHR | |
| SCHEMBL8838455 | 0.80 | ADRB2 (0.41) | TSHRHSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL9003678 | 0.80 | POLB (0.45) | GAAMAPK1CA1CA2POLB | |
| SCHEMBL17075344 | 0.75 | GAA (0.38) | HTTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8385394 | 0.73 | — | — | |
| SCHEMBL17075343 | 0.73 | MEN1 (0.34) | CA1CA2POLBCA9KMT2A | |
| SCHEMBL24246793 | 0.72 | NAAA (0.35) | TSHRKMT2AMEN1 | |
| SCHEMBL10299821 | 0.72 | MEN1 (0.33) | HTTKMT2ACYP3A4CYP2C9MEN1 | |
| SCHEMBL22154463 | 0.71 | GAA (0.33) | HTTGAAKMT2AMEN1 | |
| SCHEMBL68625 | 0.71 | CYP19A1 (0.38) | HTTGAATSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541274-A | Polymeric adducts of hindered amine-epoxides as stabilizers | CIBA-GEIGY CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |