Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9003835 | 0.99 | PPARG (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL8982072 | 0.83 | AGTR1 (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL8982071 | 0.81 | AGTR1 (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL9003683 | 0.80 | AGTR1 (0.59) | PPARGAGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9003832 | 0.79 | AGTR1 (0.58) | PPARGAGTR1AGTR2 | |
| SCHEMBL9003775 | 0.79 | PPARG (0.42) | PPARGAGTR1AGTR2 | |
| SCHEMBL9471931 | 0.77 | PTGS2 (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL28421136 | 0.74 | AGTR1 (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL9207303 | 0.71 | AGTR1 (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL9003778 | 0.71 | AGTR2 (0.45) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519143-A | Process for the isolation and purification of an imidazole stereoisomer from a mixture of stereoisomers by selective precipitation | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-21 | — | — | US | claimed |
| US-5519143-A | Process for the isolation and purification of an imidazole stereoisomer from a mixture of stereoisomers by selective precipitation | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-21 | — | — | US | disclosed |