SCHEMBL9003875

SCHEMBL9003875

COc1cccc(-c2ccc(N)c(OC)c2N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDO2 P48775 1/20 0.50
▸ CYP3A4 P08684 3/20 0.47
▸ CYP1A1 P04798 2/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ CYP2E1 P05181 2/20 0.47
▸ CYP2C8 P10632 2/20 0.47
▸ CYP2D6 P10635 2/20 0.47
▸ CYP2A6 P11509 2/20 0.47
▸ CYP2C9 P11712 2/20 0.47
▸ CYP4B1 P13584 2/20 0.47
▸ CYP2B6 P20813 2/20 0.47
▸ CYP3A5 P20815 2/20 0.47
▸ CYP2A7 P20853 2/20 0.47
▸ CYP3A7 P24462 2/20 0.47
▸ CYP2F1 P24903 2/20 0.47
▸ CYP2C18 P33260 2/20 0.47
▸ CYP2C19 P33261 2/20 0.47
▸ CYP2J2 P51589 2/20 0.47
▸ CYP4F2 P78329 2/20 0.47
▸ CYP4F8 P98187 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24330236 0.86 TDO2 (0.49) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL3490386 0.81 TDO2 (0.54) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL7205617 0.81 ALOX5AP (0.44) FYNALDH1A1LMNAKDM4EKMT2A
SCHEMBL28255761 0.80 TDO2 (0.55) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL6011438 0.77 CYP3A4 (0.58) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL28184418 0.77 CYP3A4 (0.54) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL6571024 0.77 CYP3A4 (0.58) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL30785681 0.76 TDO2 (0.55) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL396757 0.76 TDO2 (0.55) TDO2CYP3A4CYP1A1CYP1A2CYP2E1
SCHEMBL1272136 0.76 TDO2 (0.46) TDO2CYP3A4CYP1A1CYP1A2CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115362535-A UV curable resin composition suitable for redistribution layers 设计分子有限公司 2022-11-18 — — CN claimed
CN-111108144-A Curable polyimide 设计分子有限公司 2020-05-05 — — CN claimed
CN-120153462-A Adhesive film, temporary fixing material, cured product, laminate, and method for producing electronic component 积水化学工业株式会社 2025-06-13 — — CN disclosed
CN-119350563-B Polymer capable of being assembled with protein and hydrophobic small molecule medicine and preparation method thereof 至微(深圳)医学科技有限公司 2025-04-04 — — CN disclosed
CN-119350563-A Polymer capable of being assembled with protein and hydrophobic small molecule medicine and preparation method thereof 至微(深圳)医学科技有限公司 2025-01-24 — — CN disclosed
CN-118108944-A Thermosetting imide resin composition, and uncured resin film, cured resin film, prepreg, substrate, and adhesive using same 信越化学工业株式会社 2024-05-31 — — CN disclosed
CN-112673040-B Epoxy resin, epoxy resin composition, epoxy resin cured product, and composite material 株式会社力森诺科 2024-05-28 — — CN disclosed
CN-116918007-A insulated wire 住友电气工业株式会社 2023-10-20 — — CN disclosed
CN-111164125-B Epoxy resin, epoxy resin composition, epoxy resin cured product, and composite material 株式会社力森诺科 2023-09-29 — — CN disclosed
CN-116635481-A Insulated wire and method for manufacturing the same 住友电气工业株式会社 2023-08-22 — — CN disclosed
CN-111148777-B Epoxy resin, epoxy resin composition, epoxy resin cured product, and composite material 株式会社力森诺科 2023-08-11 — — CN disclosed
WO-2020009911-A1 DARK-COLOR POLYMER COMPOSITE FILMS NANOTEK INSTRUMENTS, INC. (US) 2020-01-09 — — WO disclosed
CN-110573963-A Photosensitive resin composition 日产化学株式会社 2019-12-13 — — CN disclosed
US-9351971-B2 Substituted 2,2′-biphenazines for treating diseases EUTROPICS PHARMACEUTICALS, INC. (US) 2016-05-31 — — US disclosed
US-9209444-B2 Polymide blend nanofiber and its use in battery separator JIANGXI ADVANCE NANOFIBER S&T CO., LTD. (CN) 2015-12-08 — — US disclosed
US-20150216862-A1 2,2'-BIPHENAZINE COMPOUNDS AND METHODS USEFUL FOR TREATING DISEASES EUTROPICS THERAPEUTICS, INC. 2015-08-06 — — US disclosed
US-20130164629-A1 POLYMIDE BLEND NANOFIBER AND ITS USE IN BATTERY SEPARATOR JIANGXI ADVANCE NANOFIBER S&T CO., LTD. (CN) 2013-06-27 — — US disclosed
US-5541000-A Latent, thermal cure accelerators for epoxy-aromatic amine resins having lowered peak exotherms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-07-30 — — US disclosed
EP-0610425-A1 PROCESS FOR PREPARING A POLYIMIDE FILM WITH A PRESELECTED VALUE FOR CTE. DU PONT (US) 1994-08-17 — — EP disclosed
WO-1993009167-A1 PROCESS FOR PREPARING A POLYIMIDE FILM WITH A PRESELECTED VALUE FOR CTE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150216862-A1 2,2'-BIPHENAZINE COMPOUNDS AND METHODS USEFUL FOR TREATING DISEASES MCL1, BCL3, BCL2L1 TDO2 3640/4885CYP3A4 3841/4885CYP1A1 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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