Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784155 | 0.86 | ALOX5AP (0.49) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL16738874 | 0.85 | ALOX5AP (0.48) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL24521850 | 0.83 | ALOX5AP (0.43) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL8898516 | 0.83 | NPC1 (0.45) | ALOX5APFEN1ALDH1A1PDE4BPDE4A | |
| SCHEMBL9003875 | 0.81 | TDO2 (0.50) | ALDH1A1HSD17B10MAPTFYNKDM4E | |
| SCHEMBL27833081 | 0.79 | PDE4B (0.44) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| Tannin Pyrogallol SCHEMBL7671493 | 0.79 | HSD17B10 (0.50) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3791228 | 0.78 | ALDH1A1 (0.56) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL7510969 | 0.78 | ALOX5AP (0.40) | ALOX5APFEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL7510960 | 0.78 | ALOX5AP (0.40) | ALOX5APFEN1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355619-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062307-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-15 | — | — | WO | disclosed |