Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.50 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.50 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.50 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.50 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6011564 | 0.98 | CYP3A4 (0.56) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL6571024 | 0.86 | CYP3A4 (0.58) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL3789651 | 0.86 | ALDH1A1 (0.58) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6570983 | 0.85 | ALDH1A1 (0.56) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL5685507 | 0.85 | CYP3A4 (0.56) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL2964992 | 0.85 | ACHE (0.53) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL7113080 | 0.85 | CYP3A4 (0.56) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL6011385 | 0.84 | ABL1 (0.47) | CYP3A4ALDH1A1CYP1A1CYP1A2CYP2E1 | |
| Hydrochloric Acid SCHEMBL5684599 | 0.83 | ALDH1A1 (0.55) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 | |
| SCHEMBL8862673 | 0.83 | CYP3A4 (0.55) | CYP3A4ALDH1A1TDO2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | claimed |
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-7056347-B2 | Coloring agents for keratin fibers containing (1,1′-biphenyl)-2,4-diamine derivatives in addition to novel (1,1′-biphenyl)-2,4-diamine-derivatives | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1355619-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-18 | — | — | US | disclosed |
| WO-2002062307-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | KRT18, DSP, DSG1 | CYP3A4 3726/4885ALDH1A1 120/4885TDO2 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.