Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004079 | 1.00 | MEN1 (0.64) | MEN1KMT2ACYP1A2CYP3A4ADRA2A | |
| SCHEMBL8073211 | 0.85 | MEN1 (0.59) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| Hydrochloric Acid SCHEMBL2894693 | 0.84 | MEN1 (0.57) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL25907635 | 0.83 | CES2 (0.50) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL25362682 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL8615977 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL17847415 | 0.80 | DGAT1 (0.44) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL12648575 | 0.78 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL29370768 | 0.78 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 | |
| SCHEMBL30938556 | 0.78 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733037-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015941-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |