Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.45 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004075 | 0.79 | NFE2L2 (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL9004122 | 0.75 | HTR2A (0.45) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9004126 | 0.75 | BCHE (0.49) | SMN1; SMN2LMNABCHEHTR2AHTR2C | |
| SCHEMBL9004121 | 0.75 | HTR2A (0.45) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9004115 | 0.75 | HTR2A (0.45) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9004102 | 0.71 | HTR2A (0.51) | ALDH1A1NPC1BCHEMAOBHTR2A | |
| SCHEMBL9004105 | 0.71 | BCHE (0.49) | KDM4ENPC1RAB9ALMNABCHE | |
| SCHEMBL9004163 | 0.70 | NFE2L2 (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2NFE2L2 | |
| SCHEMBL11156099 | 0.69 | KDM4E (0.61) | KDM4EALDH1A1NFE2L2BCHEHTR7 | |
| SCHEMBL11156088 | 0.69 | KDM4E (0.61) | KDM4EALDH1A1NFE2L2BCHEHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |