Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.55 |
| ▸ | TFEB | P19484 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004163 | 0.88 | NFE2L2 (0.58) | NFE2L2TFEBKDM4ETRPA1MAPT | |
| SCHEMBL9004112 | 0.79 | KDM4E (0.51) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL7897400 | 0.76 | KDM4E (0.65) | NFE2L2TFEBKDM4ETRPA1MAPT | |
| SCHEMBL7897397 | 0.76 | KDM4E (0.65) | NFE2L2TFEBKDM4ETRPA1MAPT | |
| SCHEMBL9004187 | 0.74 | TRPA1 (0.71) | TRPA1MAPTNPC1RAB9ALMNA | |
| Coumarinic Acid Methyl Ether SCHEMBL28250887 | 0.72 | NFE2L2 (0.71) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL2623834 | 0.72 | NFE2L2 (0.81) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL9004120 | 0.71 | TRPA1 (0.54) | NFE2L2TRPA1MAPTNPC1RAB9A | |
| SCHEMBL5598851 | 0.71 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 | |
| SCHEMBL5598849 | 0.71 | NFE2L2 (1.00) | NFE2L2TFEBKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| CN-1100716-A | Basic ethers and process for the preparation thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-03-29 | — | — | CN | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |