Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412227 | 1.00 | KCNH2 (0.43) | KCNH2TRPA1ACHEMAOBBCHE | |
| SCHEMBL9004142 | 0.90 | KCNH2 (0.42) | KCNH2TRPA1ACHEMAOBBCHE | |
| SCHEMBL9004115 | 0.89 | HTR2A (0.45) | KCNH2TRPA1ACHEMAOBMAPT | |
| SCHEMBL9004121 | 0.89 | HTR2A (0.45) | KCNH2TRPA1ACHEMAOBMAPT | |
| SCHEMBL9004122 | 0.89 | HTR2A (0.45) | KCNH2TRPA1ACHEMAOBMAPT | |
| SCHEMBL9004096 | 0.89 | ACHE (0.38) | KCNH2ACHEMAOBBCHEMAPT | |
| SCHEMBL9004105 | 0.88 | BCHE (0.49) | TRPA1ACHEBCHEMEN1KMT2A | |
| SCHEMBL9004100 | 0.79 | HTR2A (0.46) | TRPA1ACHEMAOBMAPTMEN1 | |
| SCHEMBL9004134 | 0.77 | CHRM1 (0.41) | KCNH2TRPA1ACHEMAOBHTR2A | |
| SCHEMBL9004076 | 0.77 | MCHR1 (0.46) | ACHEMAOBBCHELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |