Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004122 | 0.90 | HTR2A (0.45) | HTR2AHTR2CHTR2BMAPTTRPA1 | |
| SCHEMBL9004115 | 0.90 | HTR2A (0.45) | HTR2AHTR2CHTR2BMAPTTRPA1 | |
| SCHEMBL9004121 | 0.90 | HTR2A (0.45) | HTR2AHTR2CHTR2BMAPTTRPA1 | |
| SCHEMBL9004142 | 0.88 | KCNH2 (0.42) | HTR2AHTR2CHTR2BMAPTTRPA1 | |
| SCHEMBL9004102 | 0.86 | HTR2A (0.51) | HTR2AHTR2CHTR2BTRPA1NPC1 | |
| SCHEMBL9004155 | 0.86 | LMNA (0.51) | HTR2AHTR2CHTR2BNPC1LMNA | |
| SCHEMBL9412273 | 0.84 | HTR2A (0.43) | HTR2AHTR2CHTR2BMAPTNPC1 | |
| SCHEMBL9004068 | 0.80 | MAPT (0.38) | MAPTTRPA1MEN1KMT2ANPC1 | |
| SCHEMBL9004093 | 0.79 | BCHE (0.51) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL9412227 | 0.79 | KCNH2 (0.43) | HTR2AHTR2CHTR2BMAPTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |