Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004176 | 0.82 | CHRM1 (0.39) | CYP3A4HRH3SLC22A1CHRM2HTR1A | |
| SCHEMBL9004074 | 0.81 | HRH3 (0.41) | MEN1KMT2AHRH3CHRM2CHRM4 | |
| SCHEMBL9004099 | 0.80 | HRH3 (0.43) | MEN1KMT2AHRH3CHRM2CHRM4 | |
| SCHEMBL9412241 | 0.80 | HRH3 (0.43) | MEN1KMT2AHRH3CHRM2CHRM4 | |
| SCHEMBL9004170 | 0.77 | KEAP1 (0.43) | SMN1; SMN2LMNAKMT2AHRH3 | |
| SCHEMBL9412273 | 0.76 | HTR2A (0.43) | CYP3A4SMN1; SMN2LMNAHRH3HTR2A | |
| SCHEMBL9004144 | 0.74 | UTS2R (0.39) | SMN1; SMN2LMNATSHRHTR2AHTR2C | |
| SCHEMBL9004096 | 0.74 | ACHE (0.38) | SMN1; SMN2MEN1LMNAKMT2AKCNH2 | |
| SCHEMBL9004137 | 0.74 | POLB (0.44) | SMN1; SMN2MEN1KMT2ACYP2D6TSHR | |
| SCHEMBL9004191 | 0.72 | KMT2A (0.37) | SMN1; SMN2MEN1LMNAKMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | claimed |
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |