Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004141 | 0.85 | NOS3 (0.37) | KMT2AMEN1ADRB2 | |
| SCHEMBL9412212 | 0.84 | NOS3 (0.37) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL9004137 | 0.80 | POLB (0.44) | KMT2AMEN1HTTSMN1; SMN2POLB | |
| SCHEMBL9004140 | 0.79 | LMNA (0.44) | LMNAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9004070 | 0.78 | HSF1 (0.39) | LMNAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9004128 | 0.77 | KCNH2 (0.37) | KMT2AMEN1LMNAHTTMAPT | |
| SCHEMBL9004176 | 0.73 | CHRM1 (0.39) | HTT | |
| SCHEMBL9004145 | 0.72 | CYP3A4 (0.42) | KMT2AMEN1LMNAHTTADRB2 | |
| SCHEMBL9412241 | 0.71 | HRH3 (0.43) | KMT2AMEN1 | |
| SCHEMBL9004099 | 0.71 | HRH3 (0.43) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |