SCHEMBL9004292

SCHEMBL9004292

NC(=O)Cc1ncnc(N)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.46
CYP1A2 P05177 1/20 0.41
F2 P00734 1/20 0.33
CA2 P00918 1/20 0.32
ACHE P22303 2/20 0.32
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HSP90AA1 P07900 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27425530 0.80 HSP90AA1 (0.36) CYP1A2HSP90AA1BCL6
SCHEMBL11141178 0.76 CYP1A2 (0.67) HTTCYP1A2F2CA2ACHE
SCHEMBL7962293 0.74 HTT (0.47) HTTF2CA2ACHEHSP90AA1
SCHEMBL7170805 0.74
SCHEMBL27342193 0.71 CASP1 (0.34) CYP1A2ALDH1A1RAB9AHSP90AA1BCL6
SCHEMBL7084096 0.71 HTT (0.44) HTTCA2ACHELMNAALDH1A1
SCHEMBL3685983 0.70
SCHEMBL6305001 0.70
SCHEMBL29391005 0.70
SCHEMBL27899778 0.69 ADORA2A (0.34) RAB9AHSP90AA1BCL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730585-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1996-09-11 EP disclosed
US-5536835-A Etherified alkyl or arylcarbamylmethylated aminotriazines and curable compositions containing the same PPG INDUSTRIES, INC. (US) 1996-07-16 US disclosed
WO-1995014677-A1 ETHERIFIED ALKYL OR ARYLCARBAMYLMETHYLATED AMINOTRIAZINES AND CURABLE COMPOSITIONS CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1995-06-01 WO disclosed