Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428658 | 0.78 | CYP1A2 (0.43) | HTTCA2P2RX7TSHR | |
| SCHEMBL77616 | 0.78 | HTT (0.48) | HTTCA2P2RX7F2ACHE | |
| SCHEMBL9004292 | 0.74 | HTT (0.46) | HTTCA2HSP90AA1F2ACHE | |
| SCHEMBL4062783 | 0.73 | HTT (0.44) | HTTCA2TSHR | |
| SCHEMBL12527639 | 0.73 | HTT (0.53) | HTTCA2 | |
| Carbamic Acid SCHEMBL2547981 | 0.73 | GABRP (0.35) | HTTHSP90AA1P2RX7ACHE | |
| SCHEMBL4072658 | 0.73 | HTT (0.40) | HTTCA2 | |
| Urea SCHEMBL28800425 | 0.71 | P2RX7 (0.32) | HTTHSP90AA1P2RX7 | |
| SCHEMBL15331879 | 0.71 | HTT (0.42) | HTTCA2F2 | |
| SCHEMBL1484336 | 0.70 | P2RX7 (0.47) | HTTCA2HSP90AA1P2RX7ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794339-B | Preparation method of (1R, 2S) -2, 6-dimethyl-1-aminoindane | 上海朴颐化学科技有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-114929874-A | Plant colonization assay using native microbial barcodes | 皮沃特生物股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-106232620-B | Insecticidal proteins and methods of use thereof | 先锋国际良种公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114364666-A | Substituted N-phenyl-N-semicarbazides pyrimidines and salts thereof and their use as herbicides | 拜耳公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112584703-A | Thickener combinations for agrochemical (crop protection) formulations with high salt content | 拜耳公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112480088-A | Thermal activation delayed fluorescence type covalent organic framework material | 江苏海洋大学 | 2021-03-12 | — | — | CN | disclosed |
| CN-111727185-A | Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances | 拜耳公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-111448194-A | 3-amino- [1,2, 4] -triazole derivatives and their use for controlling undesired vegetation | 拜耳作物科学股份公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-105916849-B | Pyrimidinyloxybenzene derivatives as herbicides | FMC公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-106632128-A | Oxazole acetone production technology | 宁夏际华环境安全科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-100351719-C | Quasi-CW diode-pumped, solid-state UV laser system and method employing same | ELECTRO SCIENT IND INC (US) | 2007-11-28 | — | — | CN | disclosed |
| CN-1714318-A | Quasi-CW diode-pumped, solid-state UV laser system and method employing same | ELECTRO SCIENT IND INC (US) | 2005-12-28 | — | — | CN | disclosed |
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |
| CN-1173279-A | Dual-purpose high effect weed killer composition for paddy field and dry farmland | LEJI CHEMICAL PLANT ZHEJIANG P (CN) | 1998-02-18 | — | — | CN | disclosed |