SCHEMBL9004423

SCHEMBL9004423

CCN(c1ccccc1)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
TDP1 Q9NUW8 2/20 0.63
MAPT P10636 3/20 0.58
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HTT P42858 1/20 0.44
DHFR P00374 2/20 0.40
HCN1 O60741 2/20 0.39
TSHR P16473 2/20 0.39
HCN4 Q9Y3Q4 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
NR3C2 P08235 1/20 0.39
APAF1 O14727 1/20 0.39
CASP3 P42574 1/20 0.39
CASP6 P55212 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11576468 0.90 MAPT (0.56) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL796040 0.89 MAPT (0.53) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL13752166 0.86 MAPT (0.73) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL9004420 0.86 MAPT (0.49) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL7511418 0.84 MAPT (0.57) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL11639565 0.80 ALDH1A1 (0.42) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL7589406 0.78 MAPT (0.51) MAPTCRHBPCRHR2NPSR1HTT
SCHEMBL17220216 0.78 MAPT (0.69) ALDH1A1TDP1MAPTCRHBPCRHR2
SCHEMBL22356490 0.78 ALDH1A1 (0.91) ALDH1A1TDP1MAPTNPSR1HTT
SCHEMBL6633842 0.78 ALDH1A1 (1.00) ALDH1A1TDP1MAPTNPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851529-B2 Triazine ring-containing polymer, and thermoplastic article and optical part including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-12-26 US disclosed
US-20200362112-A1 TRIAZINE RING-CONTAINING POLYMER, AND THERMOPLASTIC ARTICLE AND OPTICAL PART INCLUDING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2020-11-19 US disclosed
US-5574037-A MODULATED BY SINO-ATRIAL NODE, ANTIISCHEMIC AGENT IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-11-12 US disclosed
US-5332737-A Cardiovascular disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-07-26 US disclosed
EP-0431856-A2 Heterocyclic compounds ZENECA LIMITED (GB) 1991-06-12 EP disclosed