Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900844 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL900816 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL10355133 | 0.77 | PTPRZ1 (0.41) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL7472928 | 0.76 | SMN1; SMN2 (0.40) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL16467655 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL697959 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL1009669 | 0.73 | — | — | |
| SCHEMBL1009593 | 0.72 | — | — | |
| SCHEMBL15353613 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 | |
| SCHEMBL7468239 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1TDP1PTPRZ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1356988-A | Phenoxy fluoropyrimidines | BAYER AG (DE) | 2002-07-03 | — | — | CN | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20130184465-A1 | Process for the synthesis of thio-triazolo-group containing compounds | BASF SE (DE) | 2013-07-18 | — | — | US | disclosed |
| WO-2012146535-A1 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED 2,4-DIHYDRO-[1,2,4]TRIAZOLE-3-THIONES | BASF SE (DE) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012146598-A1 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED 4-AMINO-2,4-DIHYDRO-[1,2,4]TRIAZOLE-3-THIONES | BASF SE (DE) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
| CN-101902914-A | Azolylmethyloxiranes, use thereof and compositions comprising same | BASF SE | 2010-12-01 | — | — | CN | disclosed |
| US-20100273651-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-10-28 | — | — | US | disclosed |
| EP-2235005-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009077500-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |
| CN-1356988-A | Phenoxy fluoropyrimidines | BAYER AG (DE) | 2002-07-03 | — | — | CN | disclosed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317515-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, NOX5, TET1 | KDM4E 650/4885ALDH1A1 20/4885TDP1 2342/4885 |
| US-20130184465-A1 | Process for the synthesis of thio-triazolo-group containing compounds | WEE1, SLC39A11, TST | KDM4E 3187/4885ALDH1A1 3051/4885TDP1 1080/4885 |
| US-20100273651-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, SQOR, NOX5 | KDM4E 742/4885ALDH1A1 14/4885TDP1 2759/4885 |
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, DAO, DHODH | KDM4E 718/4885ALDH1A1 25/4885TDP1 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.