Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27193044 | 0.88 | RAB9A (0.77) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL9037821 | 0.83 | RAB9A (0.53) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL23539829 | 0.82 | HTT (0.52) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL17161297 | 0.82 | LMNA (0.65) | RAB9ANPC1HTTSMN1; SMN2CA12 | |
| SCHEMBL11426554 | 0.81 | RAB9A (0.63) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL2367225 | 0.81 | KIF11 (0.65) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL30343207 | 0.81 | KIF11 (0.65) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL1894047 | 0.80 | RAB9A (0.66) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL30664572 | 0.80 | RAB9A (0.66) | RAB9ANPC1HTTSMN1; SMN2PKM | |
| SCHEMBL11320624 | 0.80 | RAB9A (0.56) | RAB9ANPC1HTTSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571843-A | Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof | INNOTHERA (FR) | 1996-11-05 | — | — | US | disclosed |
| EP-0566445-A1 | Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA (FR) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993020045-A1 | INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR THE PREPARATION OF SAME AND THEIR APPLICATION AS THERAPEUTIC AGENTS | INNOTHERA (FR) | 1993-10-14 | — | — | WO | disclosed |