Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727155 | 0.86 | NPC1 (0.43) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL9005008 | 0.85 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL9004893 | 0.78 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| Hexaethylene Glycol SCHEMBL25401683 | 0.75 | NPC1 (0.35) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL4575225 | 0.75 | FDPS (0.31) | — | |
| SCHEMBL4929286 | 0.75 | FDPS (0.31) | — | |
| SCHEMBL4574714 | 0.73 | NPC1 (0.33) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL564394 | 0.69 | NPC1 (0.38) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL31229951 | 0.69 | NPC1 (0.47) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL3995849 | 0.68 | TBXAS1 (0.37) | NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588853-B1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES | MEDIOLANUM FARMACEUTICI SRL (IT) | 1996-09-18 | — | — | EP | disclosed |
| US-5463012-A | Polycarbonates and the use thereof for the preparation of bioerosible matrices | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-10-31 | — | — | US | disclosed |
| EP-0588853-A1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES. | MEDIOLANUM FARMACEUTICI SRL (IT) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992022600-A1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1992-12-23 | — | — | WO | disclosed |