Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727155 | 0.90 | NPC1 (0.43) | NPC1RAB9AKMT2AGLAHTT | |
| SCHEMBL9005008 | 0.80 | NPC1 (0.37) | NPC1RAB9AKMT2AHTTSMN1; SMN2 | |
| Triethylene Glycol SCHEMBL9004823 | 0.78 | NPC1 (0.35) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL31229951 | 0.75 | NPC1 (0.47) | NPC1RAB9AKMT2AGLAHTT | |
| SCHEMBL5317101 | 0.72 | — | — | |
| SCHEMBL7766524 | 0.72 | ALDH1A1 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL384128 | 0.72 | ALDH1A1 (0.37) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2421717 | 0.71 | MMP9 (0.43) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL179869 | 0.71 | NPC1 (0.44) | NPC1RAB9AKMT2AGLAHTT | |
| SCHEMBL667770 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588853-B1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES | MEDIOLANUM FARMACEUTICI SRL (IT) | 1996-09-18 | — | — | EP | disclosed |
| US-5463012-A | Polycarbonates and the use thereof for the preparation of bioerosible matrices | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-10-31 | — | — | US | disclosed |
| EP-0588853-A1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES. | MEDIOLANUM FARMACEUTICI SRL (IT) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992022600-A1 | POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1992-12-23 | — | — | WO | disclosed |