Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 3/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704620 | 0.84 | PTGS2 (0.89) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL9420125 | 0.84 | PTGS2 (0.89) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL7696046 | 0.83 | PTGS2 (0.91) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL7348363 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL7352493 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL23293040 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL25760152 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL13840643 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL7356996 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 | |
| SCHEMBL27783447 | 0.81 | PTGS2 (0.64) | PTGS2PTGS1ALOX5KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508275-A | CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5318987-A | Used for prophylaxis and treats coronary, circulatory and vascular diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |