Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048278 | 0.92 | MTNR1A (0.55) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL12048354 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL12047851 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL12048630 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL12048140 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1BHSD17B2HSD17B1 | |
| SCHEMBL1134082 | 0.90 | MTNR1A (0.61) | MTNR1AMTNR1BHSD17B2HSD17B1ACHE | |
| SCHEMBL30054343 | 0.90 | MTNR1A (0.61) | MTNR1AMTNR1BHSD17B2HSD17B1ACHE | |
| SCHEMBL1134087 | 0.89 | MTNR1A (0.60) | MTNR1AMTNR1BHSD17B2HSD17B1ACHE | |
| SCHEMBL13241205 | 0.88 | HSD17B2 (0.51) | MTNR1AMTNR1BHSD17B2HSD17B1CYP11B1 | |
| SCHEMBL10042852 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BHSD17B2HSD17B1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736811-A2 | Electrophotographic imaging member and process including a charge transport layer with high charge carrier mobility | XEROX CORPORATION (US) | 1996-10-09 | — | — | EP | claimed |