Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360428 | 0.77 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL2848608 | 0.72 | KMT2A (0.41) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11110764 | 0.70 | LMNA (0.43) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11390072 | 0.70 | CA12 (0.64) | CA12CA1CA2CA9LMNA | |
| SCHEMBL3937887 | 0.69 | CA12 (0.48) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7803810 | 0.68 | KMT2A (0.51) | CA12CA1CA2CA9LMNA | |
| SCHEMBL3916656 | 0.67 | LMNA (0.68) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8530813 | 0.67 | LMNA (0.59) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9272320 | 0.67 | KMT2A (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL29579255 | 0.67 | CA12 (0.53) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513351-B1 | 2-NITROIMIDAZOLE DERIVATIVE, PRODUCTION THEREOF, AND RADIOSENSITIZER CONTAINING THE SAME AS ACTIVE INGREDIENT | POLA CHEM IND INC (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5270330-A | 2-nitroimidazole derivative, production thereof, and radiosensitizer containing the same as active ingredient | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0513351-A1 | 2-NITROIMIDAZOLE DERIVATIVE, PRODUCTION THEREOF, AND RADIOSENSITIZER CONTAINING THE SAME AS ACTIVE INGREDIENT | POLA CHEMICAL INDUSTRIES INC (JP) | 1992-11-19 | — | — | EP | disclosed |