Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198102 | 0.88 | NR3C1 (0.33) | SRD5A2SRD5A1NR3C1ARPGR | |
| SCHEMBL22917993 | 0.82 | NR3C1 (0.42) | ALDH1A1CYP3A4NR3C1ARPGR | |
| SCHEMBL24444457 | 0.82 | NR3C1 (0.42) | ALDH1A1CYP3A4NR3C1ARPGR | |
| SCHEMBL22918272 | 0.79 | CYP3A4 (0.37) | MEN1MAPTKMT2ACYP3A4ALOX15 | |
| SCHEMBL24444511 | 0.79 | CYP3A4 (0.37) | MEN1MAPTKMT2ACYP3A4ALOX15 | |
| SCHEMBL24444338 | 0.79 | CYP3A4 (0.37) | MEN1MAPTKMT2ACYP3A4ALOX15 | |
| SCHEMBL11223418 | 0.74 | PGR (0.30) | PGR | |
| SCHEMBL5925783 | 0.73 | CYP19A1 (0.43) | — | |
| SCHEMBL11231341 | 0.73 | — | — | |
| SCHEMBL6013521 | 0.72 | ALOX15 (0.30) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574317-B1 | A new process for the preparation of 20-keto, 21-alpha-hydroxy steroids and intermediates therefor | ROUSSEL UCLAF (FR) | 1996-10-09 | — | — | EP | disclosed |
| EP-0574317-A1 | A new process for the preparation of 20-keto, 21-alpha-hydroxy steroids and intermediates therefor | ROUSSEL UCLAF (FR) | 1993-12-15 | — | — | EP | disclosed |