Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005293 | 0.86 | ABCB1 (0.49) | ABCB1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL8431138 | 0.85 | MAPT (0.69) | ABCB1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL8430992 | 0.78 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL9005291 | 0.77 | ABCB1 (0.48) | ABCB1MAPTMEN1KMT2AHTR1A | |
| SCHEMBL8430999 | 0.75 | ABCB1 (0.61) | ABCB1MAPT | |
| SCHEMBL8430932 | 0.73 | ABCB1 (0.56) | ABCB1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL8433505 | 0.73 | POLB (0.63) | ABCB1MAPTKMT2ATSHR | |
| SCHEMBL8432645 | 0.73 | MAPT (0.65) | ABCB1MAPTLMNAKDM4EMEN1 | |
| SCHEMBL28965465 | 0.72 | TSHR (0.61) | MAPTLMNAMAPK1KDM4ETDP1 | |
| SCHEMBL28353455 | 0.72 | TSHR (0.61) | MAPTLMNAMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | claimed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |