Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005290 | 0.86 | ABCB1 (0.51) | ABCB1MAPTMAPK1KDM4ENPSR1 | |
| SCHEMBL8431050 | 0.82 | MAPT (0.74) | ABCB1MAPTMAPK1KDM4ENPSR1 | |
| SCHEMBL8434695 | 0.74 | L3MBTL1 (0.67) | ABCB1KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL9005296 | 0.73 | HSP90AB1 (0.51) | ABCB1MAPTKDM4EALDH1A1TP53 | |
| SCHEMBL8048603 | 0.71 | ALDH1A1 (0.61) | TDP1MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL8432590 | 0.71 | ABCB1 (0.61) | ABCB1MAPTMAPK1LMNAKMT2A | |
| SCHEMBL6281664 | 0.71 | CYP3A4 (0.59) | ABCB1KDM4ENPSR1LMNAMEN1 | |
| SCHEMBL7282636 | 0.71 | ABCB1 (0.45) | ABCB1MAPTMAPK1TDP1MEN1 | |
| SCHEMBL8432330 | 0.70 | ABCB1 (0.60) | ABCB1MAPTMAPK1LMNAKMT2A | |
| SCHEMBL8444554 | 0.70 | KMT2A (0.62) | MAPTMAPK1KDM4ENPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | claimed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |