Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005296 | 0.89 | HSP90AB1 (0.51) | ABCB1HSP90AB1TP53MAPT | |
| SCHEMBL9005292 | 0.88 | MEN1 (0.41) | ABCB1HSP90AB1MAPTMEN1KMT2A | |
| SCHEMBL8431150 | 0.86 | TP53 (0.63) | ABCB1HSP90AB1TP53MAPTMEN1 | |
| SCHEMBL9005294 | 0.78 | SLC6A9 (0.43) | ABCB1HSP90AB1TP53MAPTMEN1 | |
| SCHEMBL9005290 | 0.77 | ABCB1 (0.51) | ABCB1TP53MAPTMEN1KMT2A | |
| SCHEMBL8434402 | 0.77 | TP53 (0.53) | ABCB1HSP90AB1TP53MAPTMEN1 | |
| SCHEMBL8432829 | 0.76 | TP53 (0.65) | ABCB1HSP90AB1TP53MAPTMEN1 | |
| SCHEMBL8434409 | 0.75 | MEN1 (0.56) | ABCB1HSP90AB1TP53MAPTMEN1 | |
| SCHEMBL8430992 | 0.75 | ABCB1 (0.62) | ABCB1 | |
| SCHEMBL8430999 | 0.74 | ABCB1 (0.61) | ABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | claimed |
| JP-8325241-A | — | — | None | — | — | JP | disclosed |
| JP-H08325241-A | PIPERAZINE DERIVATIVE | SENJU PHARMACEUT CO LTD | 1996-12-10 | — | — | JP | disclosed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |