Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452740 | 1.00 | CARM1 (0.57) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL22005207 | 0.98 | CARM1 (0.58) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL25445958 | 0.95 | CARM1 (0.58) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL8447322 | 0.91 | CARM1 (0.61) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL532785 | 0.91 | CARM1 (0.61) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL3468807 | 0.91 | PARP15 (0.54) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL17737147 | 0.91 | CHRNB2 (0.59) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL2296496 | 0.88 | DRD2 (0.49) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL7604221 | 0.88 | CHRNB2 (0.55) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 | |
| SCHEMBL19399039 | 0.88 | DRD2 (0.56) | CARM1PRMT6CHRNB2CHRNA4CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579223-B1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | MITSUBISHI CHEM CORP (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5385917-A | Treating androgen dependent diseases | MITSUBISHI KASEI CORPORATION (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0579223-A1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | Mitsubishi Chemical Corporation (JP) | 1994-01-19 | — | — | EP | disclosed |