SCHEMBL2296496

SCHEMBL2296496

O=C(O)c1ccc(C(=O)OCC2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
KMT2A Q03164 3/20 0.49
PARP15 Q460N3 2/20 0.49
PARP10 Q53GL7 2/20 0.49
LMNA P02545 1/20 0.47
SRD5A2 P31213 1/20 0.46
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
CHRNB2 P17787 2/20 0.44
CHRNA4 P43681 2/20 0.44
CHRNA5 P30532 1/20 0.44
CHRNA7 P36544 1/20 0.44
MEN1 O00255 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
MAP4K4 O95819 1/20 0.44
MAPT P10636 1/20 0.44
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3468807 0.93 PARP15 (0.54) DRD2DRD4KMT2APARP15PARP10
SCHEMBL9548164 0.91 DRD2 (0.52) DRD2DRD4PARP15PARP10CARM1
SCHEMBL7452740 0.88 CARM1 (0.57) DRD2DRD4KMT2ALMNACARM1
SCHEMBL9005573 0.88 CARM1 (0.57) DRD2DRD4KMT2ALMNACARM1
SCHEMBL9764680 0.87 KMT2A (0.58) KMT2APARP15PARP10LMNAMEN1
SCHEMBL22005207 0.86 CARM1 (0.58) DRD2DRD4KMT2ALMNACARM1
SCHEMBL17737147 0.86 CHRNB2 (0.59) DRD2DRD4CARM1PRMT6CHRNB2
SCHEMBL5710011 0.85 LMNA (0.53) DRD2DRD4KMT2APARP15PARP10
SCHEMBL16381840 0.85 CHRNB2 (0.58) DRD2DRD4KMT2APARP15PARP10
SCHEMBL14882891 0.85 MMP13 (0.51) DRD2DRD4KMT2APARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030175499-A1 Compositions for imparting a translucent optical effect to transparent thermoplastic polymers U.S. BANK TRUST NATIONAL ASSOCIATION, AS SUCCESSOR CORPORATE TRUSTEE TO STATE STREET BANK AND TRUST COMPANY, N.A. 2003-09-18 US claimed
WO-1998056850-A1 CONCENTRATE COMPOSITIONS FOR IMPARTING A TRANSLUCENT OPTICAL EFFECT TO TRANSPARENT THERMOPLASTIC POLYMERS M.A. HANNACOLOR (US) 1998-12-17 WO claimed
US-4861648-A Materials for laminating flexible printed circuits GILA RIVER PRODUCTS, INC. (US) 1989-08-29 US claimed
EP-2360208-B1 RESIN COMPOSITION CONTAINING CYCLIC CARBODIMIDE TEIJIN LTD (JP) 2022-01-19 EP disclosed
US-8816018-B2 Resin composition comprising a cyclic carbodiimide TEIJIN LIMITED (JP) 2014-08-26 US disclosed
US-8592529-B2 Resin composition comprising a cyclic carbodiimide TEIJIN LIMITED (JP) 2013-11-26 US disclosed
US-20130005875-A1 RESIN COMPOSITION COMPRISING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2013-01-03 US disclosed
US-8278401-B2 Radiation or thermally curable barrier sealants HENKEL AG & CO. KGAA (DE) 2012-10-02 US disclosed
CN-101171288-B Polyester molding composition for electrical devices DSM IP ASSETS BV 2012-04-18 CN disclosed
US-20110224385-A1 RESIN COMPOSITION COMPRISING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2011-09-15 US disclosed
EP-2360208-A1 RESIN COMPOSITION CONTAINING CYCLIC CARBODIMIDE Teijin Limited (JP) 2011-08-24 EP disclosed
US-20100164368-A1 RADIATION- OR THERMALLY-CURABLE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CO (DE) 2010-07-01 US disclosed
CN-1685412-A Limited play optical media with improved shelf life and playability GEN ELECTRIC (US) 2005-10-19 CN disclosed
US-20030175499-A1 Compositions for imparting a translucent optical effect to transparent thermoplastic polymers U.S. BANK TRUST NATIONAL ASSOCIATION, AS SUCCESSOR CORPORATE TRUSTEE TO STATE STREET BANK AND TRUST COMPANY, N.A. 2003-09-18 US disclosed
WO-1998056850-A1 CONCENTRATE COMPOSITIONS FOR IMPARTING A TRANSLUCENT OPTICAL EFFECT TO TRANSPARENT THERMOPLASTIC POLYMERS M.A. HANNACOLOR (US) 1998-12-17 WO disclosed
US-4861648-A Materials for laminating flexible printed circuits GILA RIVER PRODUCTS, INC. (US) 1989-08-29 US disclosed