Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401258 | 0.81 | CREBBP (0.46) | KMOACE2CREBBPMEN1ALDH1A1 | |
| SCHEMBL4951622 | 0.80 | KMO (0.57) | KMOPTGDR2CREBBPMEN1ALDH1A1 | |
| SCHEMBL25486915 | 0.80 | ACE2 (0.50) | KMOACE2CREBBPMEN1ALDH1A1 | |
| SCHEMBL3144099 | 0.78 | ANPEP (0.38) | PTGDR2PTGDRMEN1ALDH1A1KMT2A | |
| SCHEMBL4946903 | 0.78 | KMO (0.54) | KMOPTGDR2CREBBPMEN1ALDH1A1 | |
| SCHEMBL1398501 | 0.77 | KMO (0.54) | KMOPTGDR2CREBBPMEN1ALDH1A1 | |
| SCHEMBL13957843 | 0.76 | KMO (0.57) | KMOCREBBPMEN1ALDH1A1POLB | |
| SCHEMBL11674643 | 0.76 | KMO (0.57) | KMOPTGDR2PTGDRMEN1ALDH1A1 | |
| SCHEMBL3902715 | 0.76 | KMO (0.57) | KMOPTGDR2CREBBPMEN1ALDH1A1 | |
| SCHEMBL18304697 | 0.76 | KMO (0.53) | KMOPTGDR2CREBBPSRD5A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579223-B1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | MITSUBISHI CHEM CORP (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5385917-A | Treating androgen dependent diseases | MITSUBISHI KASEI CORPORATION (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0579223-A1 | Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity | Mitsubishi Chemical Corporation (JP) | 1994-01-19 | — | — | EP | disclosed |