Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572063 | 0.95 | KMO (0.46) | KMOS1PR1L3MBTL1GAASMN1; SMN2 | |
| SCHEMBL10148085 | 0.91 | CREBBP (0.47) | KMOGAASMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL4951622 | 0.87 | KMO (0.57) | KMOS1PR1L3MBTL1GAAPTGDR2 | |
| SCHEMBL4946903 | 0.85 | KMO (0.54) | KMOS1PR1L3MBTL1GAAPTGDR2 | |
| Methyl Alcohol SCHEMBL31596316 | 0.82 | KMO (0.51) | KMOS1PR1 | |
| SCHEMBL313355 | 0.81 | KMO (0.54) | KMOL3MBTL1GAASRD5A2HSD17B10 | |
| SCHEMBL448284 | 0.81 | KMO (0.54) | KMOSRD5A2 | |
| SCHEMBL30952631 | 0.81 | KMO (0.54) | KMOSRD5A2 | |
| SCHEMBL901167 | 0.80 | KMO (0.53) | KMOL3MBTL1GAASRD5A2HSD17B10 | |
| SCHEMBL7792659 | 0.80 | CA12 (0.56) | KMOPTGDR2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307395-B1 | SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS | ISP INVESTMENTS LLC (US) | 2020-08-05 | — | — | EP | disclosed |
| US-10328003-B2 | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS LLC (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180168970-A1 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS LLC (US) | 2018-06-21 | — | — | US | disclosed |
| EP-3307395-A1 | SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS | ISP Investments LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016201260-A1 | SOLUBILIZING AGENTS FOR FUNCTIONAL ACTIVE COMPOUNDS | ISP INVESTMENTS INC. (US) | 2016-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10328003-B2 | Solubilizing agents for active or functional organic compounds | C1S, POLR1C, TYR | KMO 2068/4885S1PR1 545/4885L3MBTL1 754/4885 |
| US-20180168970-A1 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | C1S, POLR1C, TYR | KMO 2068/4885S1PR1 545/4885L3MBTL1 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.