Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ATP4A | P20648 | 4/20 | 0.45 |
| ▸ | ATP4B | P51164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257856 | 0.88 | ALDH1A1 (0.50) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL9005970 | 0.79 | PTPN2 (0.47) | ALDH1A1TP53MAPTLMNARAB9A | |
| SCHEMBL9005934 | 0.79 | MEN1 (0.46) | TP53MAPTLMNARAB9AATP4A | |
| SCHEMBL9005938 | 0.78 | TP53 (0.45) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL9005931 | 0.78 | ATP4A (0.41) | TP53MAPTRAB9AATP4AATP4B | |
| SCHEMBL9262328 | 0.76 | KDM4E (0.55) | ALDH1A1GAATP53MAPTLMNA | |
| SCHEMBL9263153 | 0.76 | NPC1 (0.53) | TP53MAPTLMNARAB9AKDM4E | |
| SCHEMBL9177249 | 0.75 | PPARA (0.61) | GAATP53MAPTLMNARAB9A | |
| SCHEMBL9266531 | 0.73 | TP53 (0.51) | TP53MAPTLMNAATP4AATP4B | |
| SCHEMBL4039765 | 0.73 | CYSLTR1 (0.53) | ALDH1A1GAATP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |